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Second messenger system - Upload, Share, and Discover Content on SlideShare BY, DAMARIS BENNY DANIEL I Msc. ZOOLOGY ... Transcript 1. BY, DAMARIS BENNY DANIEL I Msc. ZOOLOGY 2. INTRODUCTION Second messengers are molecules that relay signals from receptors on the cell ...
Second Messengers and Signal Transduction Second Messengers and Signal Transduction Tim Bloom, Ph.D. 104A Hall of Science 893-1712 Overview Signal transduction- a concept Second messengers Characteristics Examples Benefits Signal Transduction Intracellular communication Detection of ...
Second Messenger Systems - Upload, Share, and Discover Content on SlideShare Second MessengerSystemsDr. Kunal A. Chitnis2nd Yr ResidentT.N.M.C.16th July 11 ... G0- ↓ ca entry into cells Guanine exchange factors To form heterotrimer GEF- Guanine exchange factors Conformational change substrates
cGAS produces a 2[prime]-5[prime]-linked cyclic dinucleotide second messenger that activates STING : Detection of cytoplasmic DNA represents one of the most fundamental mechanisms of the innate immune system to sense the presence of microbial pathogens. Moreover, erroneous detection of endogenous DNA by the same sensing mechanisms has an important ...
Cyclic di-AMP: another second messenger enters the fray : Nature Reviews Microbiology : Nature Publi Abstract • Key points • Introduction • Synthesis of c-di-AMP • Architecture of DAC domain proteins • Degradation of c-di-AMP • c-di-AMP: an essential second messenger • c-di-AMP receptors • Other cellular processes influenced by c-di-AMP • Unresolved ...
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zReceptor on the surface can “pass” the signal to Cell-to-Cell Signaling z Second Messengers 5 Lipid derived second messengers zMade by phospholipases and lipid kinases zIn multiple step reactions (cAMP single reaction) zDifferent phospholipases cleave 4 ester bonds in phosphoglycerides zOr amide bond in sphingomyelin zYield different signaling .