JCI - The stem cell niche: tissue physiology at a single cell level Stem cells are the critical unit affecting tissue maintenance, regeneration, and repair, with particular relevance to the tissues with high cell turnover. Stem cell regulation accommodates the conflicting needs of prompt responsiveness to injury and long-
The Evolving Hematopoietic Stem Cell Niche Dr. Frenette indicated no relevant conflicts of interest. Director and Chair, Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Departments of Medicine and Cell Biology, Albert Einstein College of Medicine, Bronx,
The hematopoietic stem cell and its niche: a comparative view Abstract. Stem cells have been identified as a source of virtually all highly differentiated cells that are replenished during the lifetime of an animal. The critical ...
Osteoblastic cells regulate the haematopoietic stem cell niche. 1. Nature. 2003 Oct 23;425(6960):841-6. Osteoblastic cells regulate the haematopoietic stem cell niche. Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, Martin RP, Schipani E, Divieti P, Bringhurst FR, Milner LA, Kronenberg HM, Scadden ...
Ecological niche - Wikipedia, the free encyclopedia In ecology, a niche (CanE, UK /ˈniːʃ/ or US /ˈnɪtʃ/)[1] is a term with a variety of meanings related to the behavior of a species living under specific environmental conditions.[2] The ecological niche describes how an organism or population responds to t
Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation : Nature : Natu Haematopoietic stem and progenitor cells are maintained by special microenvironments known as niches in bone marrow. Many studies have identified diverse candidate cells that constitute niches for haematopoietic stem cells in the marrow, including osteobl
What does the concept of the stem cell niche really ... - BioMed Central 9 Mar 2012 ... The varied growth factors and cell surface molecules produced by niche cells may share the common goal of controlling stem cell pools.
Maintenance of Adult Stem Cells: Role of the Stem Cell Niche niches. Analysis of niche regulation will lead to a better understanding of stem cell behavior. Moreover, altering the cancer stem cell fate through modification of ...
Nice Neighborhood: Emerging Concepts of the Stem Cell Niche: Cell 27 Mar 2014 ... No metazoan cell survives on its own, absent the signals and support of its milieu . For multicellular life with specialized tissues to persist, ...